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There have been no expertise thus far with the use of METROGEL-VAGINAL in Expecting sufferers. Metronidazole crosses the placental barrier and enters the fetal circulation promptly. No fetotoxicity or teratogenicity was observed when metronidazole was administered orally to Expecting mice at 6 periods the encouraged human dose (based upon mg/m2); nonetheless, in one modest study where by the drug was administered intraperitoneally, some intrauterine deaths had been noticed. The connection of those findings for the drug is unidentified.
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